Somatic Primary piRNA Biogenesis Driven by cis-Acting RNA Elements and trans-Acting Yb
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چکیده
منابع مشابه
Somatic Primary piRNA Biogenesis Driven by cis-Acting RNA Elements and trans-Acting Yb.
Primary piRNAs in Drosophila ovarian somatic cells arise from piRNA cluster transcripts and the 3' UTRs of a subset of mRNAs, including Traffic jam (Tj) mRNA. However, it is unclear how these RNAs are determined as primary piRNA sources. Here, we identify a cis-acting 100-nt fragment in the Tj 3' UTR that is sufficient for producing artificial piRNAs from unintegrated DNA. These artificial piRN...
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ژورنال
عنوان ژورنال: Cell Reports
سال: 2015
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2015.06.035