Somatic cell mutations in cerebral tissue of cattle affected by bovine spongiform encephalopathy
نویسندگان
چکیده
منابع مشابه
Somatic cell mutations in cerebral tissue of cattle affected by bovine spongiform encephalopathy
In animals the prion disease includes sheep and goat scrapie and the bovine spongiform encephalopathy (BSE). While several polymorphisms of the prion (PRNP) gene have been identified in sheep and some of them have been associated with susceptibility to scrapie, few mutations are reported in cattle and no correlation with BSE have been demonstrated. Genetic screening for mutants in the PRNP gene...
متن کاملSurveillance for lesions of bovine spongiform encephalopathy in US cattle.
The appearance of bovine spongiform encephalopathy (BSE) as a new disease of cattle in 1985-1987 increased worldwide interest in various aspects of human and animal spongiform encephalopathies. In the United States, a part of the surveillance effort has been directed toward prospective examination of bovine brain specimens for lesions of BSE. One focus area has been to obtain specimens from cat...
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To the Editor: A defi nitive diagnosis of bovine spongiform encephalopathy (BSE) in cattle usually relies on Western blot and immunohistochemical testing of samples from the obex region of the brainstem. These conventional diagnostic tests can detect the presence of the abnormal (disease-associated) form of the prion protein (PrPSc) in brain samples several months before the onset of clinical s...
متن کاملBovine spongiform encephalopathy.
A detailed account is given of the occurrence of bovine spongiform encephalopathy (BSE), current research into the aetiology of this new disease of cattle, and the relationship between BSE, scrapie and other similar diseases. Epidemiology, clinical signs, pathology, diagnosis, prevention and control are described.
متن کاملBovine Spongiform Encephalopathy
Bovine spongiform encephalopathy (BSE) is a fatal neurodegenerative disease, caused by a prion, that mainly affects cattle. Other ruminant species, cats, non-human primates and humans are occasionally affected; this disease is called feline spongiform encephalopathy (FSE) in cats, and variant Creutzfeldt–Jakob disease (vCJD) in people. BSE is a relatively new disease that was first reported in ...
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ژورنال
عنوان ژورنال: Agricultural Sciences
سال: 2010
ISSN: 2156-8553,2156-8561
DOI: 10.4236/as.2010.11005