Solution structure of the potassium channel inhibitor agitoxin 2: Caliper for probing channel geometry
نویسندگان
چکیده
منابع مشابه
Agitoxin Footprinting the Shaker Potassium Channel Pore
In voltage-dependent K+ channels, each of the four identical subunits contributes one pore loop to the central ion selectivity unit at the interface between the subunits. The pore loop is also the target for scorpion venom peptide inhibitors. These inhibitors bind at the pore entryway between the four subunits and can assume any one of four orientations. The orientations become distinguishable ...
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ژورنال
عنوان ژورنال: Protein Science
سال: 1995
ISSN: 0961-8368,1469-896X
DOI: 10.1002/pro.5560040805