Solution processed low power organic field-effect transistor bio-chemical sensor of high transconductance efficiency

Abstract Developing organic field-effect transistor (OFET) biosensors for customizable detection of biomarkers many diseases would provide a low-cost and convenient tool both biological studies clinical diagnosis. In this work, design principles the OFET transducer were derived to relate signal-to-noise ratio ( SNR ) device-performance parameters. Steep subthreshold swing SS ), proper threshold voltage V th good-enough bias-stress stability, mechanical durability are shown be key prerequisites realizing bio-sensors high transconductance efficiency g m / I D large . Combining low trap-density channel high- k /low- gate dielectric layer, low-temperature (<100 °C) solution-processed flexible OFETs can meet performance requirements maximize An extended gate-structure biosensor was further implemented label-free miR-21, achieving limit below 10 pM with selectivity at operation (<1 V).