Solute partitioning and filtration by extracellular matrices
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چکیده
منابع مشابه
Solute partitioning and filtration by extracellular matrices.
The physiology of glomerular filtration remains mechanistically obscure despite its importance in disease. The correspondence between proteinuria and foot process effacement suggests podocytes as the locus of the filtration barrier. If so, retained macromolecules ought to accumulate at the filtration barrier, an effect called concentration polarization. Literature data indicate macromolecule co...
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While it is self-evident that all extracellular molecules are an integral part of a multicellular organism, it is paradoxical that they are often considered to be dissociated from cells. The reality is that a continuum of dynamic, bi-directional interactions links the intracellular environment through cell-surface receptors to multimolecular extracellular assemblies. These interactions not only...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Renal Physiology
سال: 2009
ISSN: 1931-857X,1522-1466
DOI: 10.1152/ajprenal.00162.2009