Soluble FAS Ligand: A Discriminating Feature between Drug-Induced Skin Eruptions and Viral Exanthemas
نویسندگان
چکیده
منابع مشابه
Serum soluble fas ligand levels and peripheral blood lymphocyte subtypes in patients with drug induced maculopapular rashes, dress and viral exanthemas
Background Fas/Fas ligand (FasL)-dependent apoptotic pathway was reported to be involved in the pathogenesis of drug induced maculopapular rashes (MPRs). In this study, we investigated serum soluble FasL level to discriminate drug-induced skin reactions from other clinically resembling skin diseases such as exanthematous viral infections. We also eveluated the role of T cells in various drug-in...
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Exanthematous reactions with various morphological and localization patterns are the most frequently encountered adverse drug reactions involving the skin. The time course of benign exanthemas typically encompasses a few days to some weeks. They are not complicated by severe systemic symptoms or internal organ involvement. They manifest themselves in a polymorphous manner with primary effloresc...
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Allergic reaction to insulin preparations seemed to have decreased since the introduction of contaminant-free, human preparations. The role of protamine sulfate in decreasing the prevalence of allergy is unclear. This study examines the causative components of insulin allergy along with the value of skin tests for diagnosis. Eleven patients with insulin allergy and 53 patients receiving insulin...
متن کاملAqueous Humor Levels of Soluble Fas and Fas-ligand in Patients with Primary Open Angle and Pseudoex-foliation Glaucoma
Background: Glaucoma is one of the most common causes of blindness and is usually associated with elevated intraocular pressure. In patients with primary open angle glau-coma the number of trabecular meshwork cells is decreased. Death of the trabecular meshwork cells may be a result of apoptosis. Objective: To investigate the aqueous humor levels of soluble Fas (sFas) and Fas-Ligand (sFasL) in ...
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Adverse cutaneous reactions are known to occur with psychotropic medications, which may lead to poor drug compliance. As compared to other group of psychotropics, there is relatively scarce literature on olanzapine-induced skin eruptions. We present a case of a 39-year-old man diagnosed with first episode mania and alcohol dependence syndrome who was started on tablet olanzapine which leads to ...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2007
ISSN: 0022-202X
DOI: 10.1038/sj.jid.5700648