منابع مشابه
Solubilization pdf
PURPOSE: Micellar solubilization is a powerful alternative for. Done regarding solubilization of drugs by micelles is presented. Abstract: In this paper, the use of surfactants for solubilization of. solubilization techniques pdf Polyelectrolytes, pH, and temperature on dye solubilization has been.Solution chemistry, solubility and solubilization. Dissolution limited bioavailability is a very c...
متن کاملSolubilization of Peptides
ity. The amino acid composition will provide a fi rst indication: before choosing a solvent, the sequence should be studied and the number of acidic, basic and neutral residues should be determined. The side-chain functionalities of acidic and basic amino acids will be charged at physiological pH. The nature of the Nand the C-terminal functionality has to be taken into consideration. The neutra...
متن کاملSolubilization of vorinostat by cyclodextrins.
BACKGROUND Vorinostat (suberoylanilide hydroxamic acid) is the first histone deacetylase inhibitor approved by US FDA for use in oncology. However, as a hydrophobic acid, its limited aqueous solubility poses a problem for parenteral delivery. Such limited solubility may also affect its oral bioavailability. OBJECTIVE The aim of this study was to evaluate whether cyclodextrins (CDs), common ex...
متن کاملSolubilization of functional calcitonin receptors.
Calcitonin (CT) binding activity has been extracted from a membrane fraction of human placenta using the zwitterionic detergent, 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulphonic acid (Chaps). Approximately two-thirds of the available binding sites were extracted using 5 mM-Chaps. The binding characteristics of 125I-labelled salmon CT(125I-sCT) to the solubilized extract were similar to...
متن کاملP11: The Effect of Flavonoids in Memory
Flavonoids may exert particularly powerful actions on mammalian cognition and may reverse age-related declines in memory and learning. Flavonoids can be modulated neuronal function and there by influencing memory, learning and cognitive function. Dietary supplementation with flavonoid-rich foods, such as blueberry, green tea and Ginkgo biloba lead to significant reversals of age-related deficit...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1951
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.71.12_1488