Solubilization by polysoaps

Solubilization of vorinostat by cyclodextrins.

BACKGROUND Vorinostat (suberoylanilide hydroxamic acid) is the first histone deacetylase inhibitor approved by US FDA for use in oncology. However, as a hydrophobic acid, its limited aqueous solubility poses a problem for parenteral delivery. Such limited solubility may also affect its oral bioavailability. OBJECTIVE The aim of this study was to evaluate whether cyclodextrins (CDs), common ex...

Solubilization of Herbicides by Single and Mixed

Membrane solubilization by detergent: resistance conferred by thickness.

The commonly held model for membrane dissolution by detergents/surfactants requires lipid transport from the inner to the outer bilayer leaflet ('flip-flop'). Although applicable to many systems, it fails in cases where cross-bilayer transport of membrane components is suppressed. In this paper we investigate the mechanism for surfactant-induced solubilization of polymeric bilayers. To that end...

Solubilization pdf

PURPOSE: Micellar solubilization is a powerful alternative for. Done regarding solubilization of drugs by micelles is presented. Abstract: In this paper, the use of surfactants for solubilization of. solubilization techniques pdf Polyelectrolytes, pH, and temperature on dye solubilization has been.Solution chemistry, solubility and solubilization. Dissolution limited bioavailability is a very c...

Optimum conditions for protein extraction from tuna processing by-products using isoelectric solubilization and precipitation processes

The by-product from tuna processing is a potential source of edible protein. Therefore, it is very important to extract protein from such raw materials for human food. In this study the optimum pH for protein extraction from tuna by-products was optimized by using isoelectric solubilization and precipitation processes. The Response Surface Methodology (RSM) and the single factor model were used...