Solid lipid dispersion of calcitriol with enhanced dissolution and stability
نویسندگان
چکیده
منابع مشابه
Cefdinir Solid Dispersion Composed of Hydrophilic Polymers with Enhanced Solubility, Dissolution, and Bioavailability in Rats.
The aim of this work was to develop cefdinir solid dispersions (CSDs) prepared using hydrophilic polymers with enhanced dissolution/solubility and in vivo oral bioavailability. CSDs were prepared with hydrophilic polymers such as hydroxypropyl-methylcellulose (HPMC; CSD1), carboxymethylcellulose-Na (CMC-Na; CSD2), polyvinyl pyrrolidone K30 (PVP K30; CSD3) at the weight ratio of 1:1 (drug:polyme...
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Combinational approach using solid dispersion and semi-solid matrix technology to enhance in vitro dissolution of telmisartan
The present investigation was focused to formulate semi-solid capsules (SSCs) of hydrophobic drug telmisartan (TLMS) by encapsulating semi-solid matrix of its solid dispersion (SD) in HPMC capsules. The combinational approach was used to reduce the lag time in drug release and improvise its dissolution. SDs of TLMS was prepared using hot fusion method by varying the combinations of Pluronic-F68...
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ژورنال
عنوان ژورنال: Asian Journal of Pharmaceutical Sciences
سال: 2013
ISSN: 1818-0876
DOI: 10.1016/j.ajps.2013.07.005