Soft tissue tumors: Dermatofibrosarcoma protuberans

Apo D in soft tissue tumors: a novel marker for dermatofibrosarcoma protuberans.

Using gene microarray expression profiling, we previously found that apolipoprotein D (Apo D) was highly expressed in dermatofibrosarcoma protuberans (DFSP). In this study, we confirm that Apo D is highly and relatively specifically expressed in DFSP using immunohistochemistry. A tissue microarray containing 421 soft tissue tumors was constructed and stained with antibodies against Apo D and CD...

Dermatofibrosarcoma protuberans.

Overview The NCCN Non-Melanoma Skin Cancer Panel has developed these guidelines outlining the treatment of dermatofibrosarcoma protuberans (DFSP) to supplement their other guidelines (NCCN Clinical Practice Guidelines in Oncology [NCCN Guidelines] for Basal Cell and Squamous Cell Skin Cancers and Merkel Cell Carcinoma; to view the most recent version of these guidelines, visit the NCCN Web site...

Dermatofibrosarcoma Protuberans in Childhood

Fibrosarcomatous dermatofibrosarcoma protuberans: A case report of an aggressive soft tissue sarcoma

Dermatofibrosarcoma protuberans is a rare soft tissue neoplasm arising from mesenchymal cells, making up about 6% of all soft tissue tumours. Often found on the scalp, neck, trunk and extremities, it has an intermediateto low-grade malignancy potential except the fibrosarcomatous variant (high-grade), which is more likely to metastasize than other types. Here we present the case of a 46-year-ol...

Dermatofibrosarcoma protuberans in childhood.

Dermatofibrosarcoma protuberans (DFSP) is a rare cutaneous tumor with a possibly misleading presentation. It is rare in childhood. We report an 18-month-old child with an acquired atrophic plaque of the left ankle. Based on clinical findings, initial proposed diagnoses included localized scleroderma and localized lipoatrophy. At the age of 5 years the plaque had increased in size and become a p...