SOFA score and acetaminophen-induced acute liver failure
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چکیده
منابع مشابه
Use of acetylcysteine for non-acetaminophen-induced acute liver failure.
The purpose of this review was to evaluate the effectiveness of acetylcysteine in the treatment of acute liver failure not related to acetaminophen. A search of MEDLINE April 2003 through May 2012 using the Pub Med database was conducted using the keywords acetylcysteine and non-acetaminophen-induced acute liver failure or acetylcysteine and liver failure. All human case reports, case series, a...
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Severe acetaminophen hepatotoxicity frequently leads to acute liver failure (ALF). We determined the incidence, risk factors, and outcomes of acetaminophen-induced ALF at 22 tertiary care centers in the United States. Detailed prospective data were gathered on 662 consecutive patients over a 6-year period fulfilling standard criteria for ALF (coagulopathy and encephalopathy), from which 275 (42...
متن کاملAcute liver failure including acetaminophen overdose.
Acute liver failure (ALF) is a dramatic, highly unpredictable clinical syndrome defined by the sudden onset of coagulopathy and encephalopathy. Acetaminophen overdose, the leading cause of ALF in the United States, has a 66% chance of recovery with early N-acetylcysteine treatment and supportive care. Cerebral edema and infectious complications are difficult to detect and treat in these patient...
متن کاملMELD score: utility and comparison with King's College criteria in non-acetaminophen acute liver failure.
OBJECTIVE To compare Model for End-stage Liver Disease Score (MELD Score, MS) and King's College Hospital (KCH) criteria for finding correlation of mortality in non-acetaminophen induced acute liver failure (NAI-ALF). STUDY DESIGN An analytical cross-sectional study. PLACE AND DURATION OF STUDY The Aga Khan University Hospital, Karachi, from 2005 to 2007. METHODOLOGY The study included pa...
متن کاملArtificial liver support in pigs with acetaminophen-induced acute liver failure
AIM To establish a reversible porcine model of acute liver failure (ALF) and treat it with an artificial liver system. METHODS Sixteen pigs weighing 30-35 kg were chosen and administered with acetaminophen (APAP) to induce ALF. ALF pigs were then randomly assigned to either an experimental group (n = 11), in which a treatment procedure was performed, or a control group (n = 5). Treatment was ...
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ژورنال
عنوان ژورنال: Liver Transplantation
سال: 2012
ISSN: 1527-6465
DOI: 10.1002/lt.23388