SODIUM TUNGSTATE

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Realization of Synergism in Sodium Tungstate-Zn

The aim of this present work is to study, the corrosion behavior of carbon steel in well water in the presence of sodium tungstate (ST)-Zn 2+ -N-(phosphenomethyl) iminodiaceticacid (NPMIDA) solutions. Electrochemical studies and FTIR spectral studies and weight loss study have been employed. It was found that the inhibition efficiency (IE) of ST (50 ppm)-Zn 2+ (10 ppm) was improved from 8% to 8...

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Interaction of rat liver glucocorticoid receptor with sodium tungstate.

Effects of sodium tungstate on various properties of rat liver glucocorticoid receptor were examined at pH7 and pH 8. At pH 7, [3H]triamcinolone acetonide binding in rat liver cytosol preparations was completely blocked in the presence of 10--20 mM-sodium tungstate at 4 degrees C, whereas at 37 degrees C a 30 min incubation of cytosol receptor preparation with 1 mM-sodium tungstate reduced the ...

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Modulation of glucose transporters in rat diaphragm by sodium tungstate.

Oral administration of sodium tungstate is an effective treatment for diabetes in animal models. We examined the effects of 6 weeks of oral administration of tungstate on glucose transporters (GLUT) in streptozotocin-induced diabetic rat diaphragm. Diabetes decreased GLUT4 expression while tungstate treatment normalized not only GLUT4 protein but also GLUT4 mRNA in the diabetic rats. Furthermor...

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Role of sodium tungstate as a potential antiplatelet agent

PURPOSE Platelet inhibition is a key strategy in the management of atherothrombosis. However, the large variability in response to current strategies leads to the search for alternative inhibitors. The antiplatelet effect of the inorganic salt sodium tungstate (Na2O4W), a protein tyrosine phosphatase 1B (PTP1B) inhibitor, has been investigated in this study. METHODS Wild-type (WT) and PTP1B k...

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Preclinical and Clinical Studies for Sodium Tungstate: Application in Humans

Diabetes is a complex metabolic disorder triggered by the deficient secretion of insulin by the pancreatic β-cell or the resistance of peripheral tissues to the action of the hormone. Chronic hyperglycemia is the major consequence of this failure, and also the main cause of diabetic problems. Indeed, several clinical trials have agreed in that tight glycemic control is the best way to stop prog...

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ژورنال

عنوان ژورنال: The Professional Medical Journal

سال: 2018

ISSN: 1024-8919,2071-7733

DOI: 10.29309/tpmj/18.4256