Sodium Dodecyl Sulfate and C31G as Microbicidal Alternatives to Nonoxynol 9: Comparative Sensitivity of Primary Human Vaginal Keratinocytes
نویسندگان
چکیده
منابع مشابه
Sodium dodecyl sulfate and C31G as microbicidal alternatives to nonoxynol 9: comparative sensitivity of primary human vaginal keratinocytes.
A broad-spectrum vaginal microbicide must be effective against a variety of sexually transmitted disease pathogens and be minimally toxic to the cell types found within the vaginal epithelium, including vaginal keratinocytes. We assessed the sensitivity of primary human vaginal keratinocytes to potential topical vaginal microbicides nonoxynol-9 (N-9), C31G, and sodium dodecyl sulfate (SDS). Dir...
متن کاملComparative in vitro sensitivities of human immune cell lines, vaginal and cervical epithelial cell lines, and primary cells to candidate microbicides nonoxynol 9, C31G, and sodium dodecyl sulfate.
In experiments to assess the in vitro impact of the candidate microbicides nonoxynol 9 (N-9), C31G, and sodium dodecyl sulfate (SDS) on human immune and epithelial cell viability, cell lines and primary cell populations of lymphocytic and monocytic origin were generally shown to be equally sensitive to exposures ranging from 10 min to 48 h. However, U-937 cells were more sensitive to N-9 and C3...
متن کاملAre there alternatives to nonoxynol-9 spermicide?
You're certainly not alone in your interest of this method. Spermicide is a popular option for birth control because it is easily accessible, simple to use, and provides added lubrication. Results from recent scientific studies for newer alternatives look promising, but more research is still needed. Some of the new ingredients being studied that may be able to function as spermicide (and provi...
متن کاملBacterial Utilization of Sodium Dodecyl Sulfate
SDS is widely used detergent in house holds and Industry. It is known to be toxic to fishes and also to animals. In the present review, we have emphasized on biodegradation of this detergent by bacteria, the pathway of biodegradation and also the enzymes involved in the degradation.
متن کاملToxicological effects of sodium dodecyl sulfate
The mass production and application of chemicals in different areas of plant and animal sciences cause a serious contamination to the immediate environment. Sodium Dodecyl Sulfate (SDS) is also known as Sodium Lauryl Sulfate (SLS) and commonly used in household, kitchen and laundry uses as a detergent ingredient and others. The description of SDS is important because it is now entered into the ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2000
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.44.7.1954-1960.2000