Sodium Alginate Nanoparticles of Isoniazid: Preparation and Evaluation
نویسندگان
چکیده
منابع مشابه
Preparation and in-vitro evaluation of sodium alginate microspheres containing diphtheria toxoid as new vaccine delivery
During last two decades, polysaccharides such as alginate (Alg) alone and in combination with other biopolymers are widely used in vaccine and drug delivery systems. The aim of the present work was to investigate the potential utility of microparticles made of alginate (Alg) as new vehicles for improving nasal vaccine delivery. For this purpose, diphtheria toxoid (DT) was chosen as a model an...
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Solid lipid nanoparticles (SLNs) are an alternative carrier system used to load the drug for targeting, to improve the bioavailability by increasing its solubility, and protecting the drug from presystemic metabolism. The avoidance of presystemic metabolism is due to the nano-metric size range, so that the liver cannot uptake the drug from the delivery system and is not metabolized by the liver...
متن کاملSynthesis of thiolated chitosan and preparation nanoparticles with sodium alginate for ocular drug delivery
PURPOSE The goal of the present study was to synthesize mucoadhesive polymer - thiolated chitosan (TCS) from chitosan (CS), then prepared CS/TCS-sodium alginate nanoparticles (CS/TCS-SA NPs), determined which was more potential for ocular drug delivery. METHODS A new method for preparing TCS was developed, and the characteristics were determined using Fourier transform infrared spectroscopy a...
متن کاملPreparation and Evaluation of Sustained Release Microsphere of Norfloxacin Using Sodium Alginate
Oral controlled drug delivery systems represent the most popular form of sustained drug delivery systems for the obvious advantages of oral route of drug administration. Such systems release the drug with constant or variable release rates. The oral controlled release systems shows a typical pattern of drug release in which the drug concentration is maintained in the therapeutic window for a pr...
متن کاملpreparation and in-vitro evaluation of sodium alginate microspheres containing diphtheria toxoid as new vaccine delivery
during last two decades, polysaccharides such as alginate (alg) alone and in combination with other biopolymers are widely used in vaccine and drug delivery systems. the aim of the present work was to investigate the potential utility of microparticles made of alginate (alg) as new vehicles for improving nasal vaccine delivery. for this purpose, diphtheria toxoid (dt) was chosen as a model anti...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutical Sciences and Drug Research
سال: 2019
ISSN: 0975-248X
DOI: 10.25004/ijpsdr.2019.110616