SnapShot: Selective Autophagy
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SnapShot: Selective Autophagy
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1Department of Cell Biology and Institute of Biomembranes, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands 2Protein Metabolism Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan 3BioScience Center, San Diego State University, San Diego, CA 92182, USA 4Department of Biochemistry, Institute of Basic Medical Sciences, University of Oslo, 0317 Oslo,...
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Autophagy has long been thought to be an essential but unselective bulk degradation pathway. However, increasing evidence suggests selective autophagosomal turnover of a broad range of substrates. Bifunctional autophagy receptors play a key role in selective autophagy by tethering cargo to the site of autophagosomal engulfment. While the identity of molecular components involved in selective au...
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ژورنال
عنوان ژورنال: Cell
سال: 2013
ISSN: 0092-8674
DOI: 10.1016/j.cell.2013.01.004