Small intestinal MUC2 synthesis in human preterm infants

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Small intestinal MUC2 synthesis in human preterm infants.

Mucin 2 (MUC2) is the structural component of the intestinal protective mucus layer, which contains high amounts of threonine in its peptide backbone. MUC2 synthesis rate might be a potential parameter for intestinal barrier function. In this study, we aimed to determine whether systemic threonine was used for small intestinal MUC2 synthesis and to calculate the MUC2 fractional synthetic rate (...

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Transpyloric feeding in small preterm infants.

Wolfsdorf, J., Makarawa, S., Fernandes, C., Fenner, A. (1975). Archives of Disease in Childhood, 50, 723. Transpyloric feeding in small preterm infants. In 20 preterm infants, birthweight ranging from 775 to 1540 g, transpyloric feeding was carried out using expressed human milk as the sole nutrient (study group). 10 further infants, birthweight range 910-1500 g, were also fed with human milk v...

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Rachitic respiratory distress in small preterm infants.

A syndrome of subacute respiratory distress, severe metabolic bone disease affecting the thoracic cage, and mild cholestasis occurred in 4 small preterm infants during the first three months of life and was associated with considerable morbidity. The early radiological features in the chest resembled thos of the Mikity-Wilson syndrome, with which the disorder may be confused. After spontaneous ...

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Characteristic Radiological findings in Preterm Infants with Missed Intestinal Perforation

BACKGROUND Pneumoperitoneum on radiological imaging is typical in intestinal perforation in necrotizing enterocolitis [NEC]. However, it is not seen in all cases and intestinal perforation is missed on occasions. We present a series of preterm infants with characteristic x-ray findings that on exploration revealed missed intestinal perforation. METHODS Retrospective review of neonates with in...

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Role of Intestinal Microflora on Necrotizing Enterocolitis in Preterm Infants

Despite overall decreasedmortality andmorbidity in preterm very low-birth-weight (VLBW:<1,500 g) infants over the past decades, necrotizing enterocolitis (NEC), a devastating emergency intestinal disease in preterm VLBW infants, remains 5 to 6% and even increase despite much effort on peri-postnatal care.1 More worrisome, approximately 20 to 30% of VLBW infants with NECwill die2 and the remaini...

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ژورنال

عنوان ژورنال: American Journal of Physiology-Gastrointestinal and Liver Physiology

سال: 2009

ISSN: 0193-1857,1522-1547

DOI: 10.1152/ajpgi.90444.2008