Sleeping Sickness Disrupts the Sleep-Regulating Adenosine System
نویسندگان
چکیده
منابع مشابه
Buprenorphine disrupts sleep and decreases adenosine concentrations in sleep-regulating brain regions of Sprague Dawley rat.
BACKGROUND Buprenorphine, a partial μ-opioid receptor agonist and κ-opioid receptor antagonist, is an effective analgesic. The effects of buprenorphine on sleep have not been well characterized. This study tested the hypothesis that an antinociceptive dose of buprenorphine decreases sleep and decreases adenosine concentrations in regions of the basal forebrain and pontine brainstem that regulat...
متن کاملSleeping sickness and the central nervous system.
Chronic African trypanosomiasis is associated with progressive behavioural deficits, for which there is a complex underlying central nervous system (CNS) pathology. This has been extensively studied in man and a range of experimental animals. An initial meningitis, which can occur quite early in the infection, is followed by a breakdown of the choroid plexus, movement of the parasite into certa...
متن کاملSleeping Sickness in Travelers - Do They Really Sleep?
The number of imported Human African Trypanosomiasis (HAT) cases in non-endemic countries has increased over the last years. The objective of this analysis is to describe the clinical presentation of HAT in Caucasian travelers. Literature was screened (MEDLINE, Pubmed) using the terms "Human African Trypanosomiasis", "travelers" and "expatriates"; all European languages except Slavic ones were ...
متن کاملSleeping Sickness Wakes Again
Sleeping sickness of horses was, as reeentiy as the IQSO's, the most devastating livestock disease in the United States. Horses died by the hundreds of thousands in the Midwestern United States, in California, and along the Atlantic seaboard at a period which coincided with the beginning of the sharp decline in the use of horses on the farm. Losses were so severe in some areas that the inevitab...
متن کاملThe Sleeping Sickness of Uganda
34 cases by the same method and found the Trypanosoma in 20 cases, or 70 per cent. An examination of 12 cases of other diseases including three of Trypanosoma fever in the same way gave negative results. The matter was then taken up by" Lieutenant-Colonel David Bruce, F.n.c.s., R A M C and Dr. David N. Nabarro, who had been deputed by the Royal Society to investigate sleeping sickness, and arri...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 2020
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.1046-20.2020