Skull Base Chordomas: Management and Results
نویسندگان
چکیده
منابع مشابه
Chordomas of the skull base: MR features.
PURPOSE To characterize the MR features of skull base chordomas with regard to signal intensity, size, position, extension, and Gd-DTPA enhancement. PATIENTS AND METHODS The MR imaging studies of 28 patients with surgically proven chordomas of the skull base were retrospectively reviewed. Twenty-two of these patients received intravenous administration of Gd-DTPA. RESULTS On short TR/short ...
متن کاملTumor-biology and current treatment of skull-base chordomas.
Chordomas are rare, slow growing tumors of the axial skeleton, which derive from the remnants of the fetal notochord. They can be encountered anywhere along the axial skeleton, most commonly in the sacral area, skull base and less commonly in the spine. Chordomas have a benign histopathology but exhibit malignant clinical behavior with invasive, destructive and metastatic potential. Genetic and...
متن کاملProton beam therapy in the management of skull base chordomas: systematic review of indications, outcomes, and implications for neurosurgeons.
BACKGROUND Chordomas are rare tumours affecting the skull base. There is currently no clear consensus on the post-surgical radiation treatments that should be used after maximal tumour resection. However, high-dose proton beam therapy is an accepted option for post-operative radiotherapy to maximise local control, and in the UK, National Health Service approval for funding abroad is granted for...
متن کاملProton radiation therapy for chordomas and chondrosarcomas of the skull base.
OBJECT Local tumor control, patient survival, and treatment failure outcomes were analyzed to assess treatment efficacy in 58 patients in whom fractionated proton radiation therapy (RT) was administered for skull base chordomas and chondrosarcomas. METHODS Between March 1992 and January 1998, a total of 58 patients who could be evaluated were treated for skull base tumors, 33 for chordoma and...
متن کاملOutcome of Clival Chordomas after Skull Base Surgeries with Mean Follow-up of 10 Years.
BACKGROUND AND OBJECTIVE Skull base chordomas are clinically malignant because of the difficulty of total removal, high recurrence rate, and occasional drop metastasis. Although aggressive surgical resection and postoperative radiation have been recommended, the long-term outcome remains unsatisfactory. METHODS From 1992 to 2011, we treated 24 patients with skull base chordoma using aggressiv...
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ژورنال
عنوان ژورنال: Neurologia medico-chirurgica
سال: 2006
ISSN: 0470-8105,1349-8029
DOI: 10.2176/nmc.46.118