Skeletal Muscle Strength and Functional Ability in Older Adults Following 10 Days of Bed Rest
نویسندگان
چکیده
منابع مشابه
Effect of 10 days of bed rest on skeletal muscle in healthy older adults.
1. Lee JK, Grace KA, Taylor AJ. Effect of a pharmacy care program on medication adherence and persistence, blood pressure, and low density lipoprotein cholesterol: a randomized controlled trial. JAMA. 2006;296:2563-2571. 2. Naylor CD. Clinical decisions: from art to science and back again. Lancet. 2001; 358:523-524. 3. Whelton PK, Appel LJ, Espeland MA, et al; TONE Collaborative Research Group....
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Bed rest induces significant loss of leg lean mass in older adults. Systemic and tissue inflammation also accelerates skeletal muscle loss, but it is unknown whether inflammation is associated to inactivity-induced muscle atrophy in healthy older adults. We determined if short-term bed rest increases toll-like receptor 4 (TLR4) signaling and pro-inflammatory markers in older adult skeletal musc...
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BACKGROUND Loss of muscle mass due to prolonged bed rest decreases functional capacity and increases hospital morbidity and mortality in older adults. OBJECTIVE To determine if HMB, a leucine metabolite, is capable of attenuating muscle decline in healthy older adults during complete bed rest. DESIGN A randomized, controlled, double-blinded, parallel-group design study was carried out in 24...
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Ten healthy sedentary subjects underwent 35-days bed rest (BR) and needle biopsy samples of the vastus lateralis muscle were collected pre-BR and post-BR. One portion of the biopsy was glycerinated and used to dissect individual muscle fibers, which were studied for measuring fiber size, myosin content and myosin actin ratio by quantitative electrophoresis. Another portion of the biopsy was imm...
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A functional evaluation of skeletal muscle oxidative metabolism during dynamic knee extension (KE) incremental exercises was carried out following a 35-day bed rest (BR) (Valdoltra 2008 BR campaign). Nine young male volunteers (age: 23.5 ± 2.2 yr; mean ± SD) were evaluated. Pulmonary gas exchange, heart rate and cardiac output (by impedance cardiography), skeletal muscle (vastus lateralis) frac...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2006
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.20.4.a382-c