Sirtuin‐1 in immunotherapy: A Janus‐headed target
نویسندگان
چکیده
منابع مشابه
Study of NGEP expression in androgen sensitive prostate cancer cells: A potential target for immunotherapy
Background: Prostate cancer is one of the leading causes of cancer deaths among men. New gene expressed in prostate (NGEP), is a prostate-specific gene expressed only in normal prostate and prostate cancer tissue. Because of its selective expression in prostate cancer cell surface, NGEP is a potential immunotherapeutic target. To target the NGEP in prostate cancer, it is essential to investig...
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Mesothelin is a differentiation antigen present on normal mesothelial cells and overexpressed in several human tumors, including mesothelioma and ovarian and pancreatic adenocarcinoma. The mesothelin gene encodes a precursor protein that is processed to yield the 40-kDa protein, mesothelin, attached to the cell membrane by a glycosylphosphatidyl inositol linkage and a 31-kDa shed fragment named...
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Mesothelin is a differentiation antigen present on normal mesothelial cells and overexpressed in several human tumors, including mesothelioma and ovarian and pancreatic adenocarcinoma. The mesothelin gene encodes a precursor protein that is processed to yield the 40-kDa protein, mesothelin, attached to the cell membrane by a glycosylphosphatidyl inositol linkage and a 31-kDa shed fragment named...
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To the Editor: The Perspective by Hassan et al. (1) is an excellent synopsis of the substantial studies by these authors and others that have identified mesothelin as a new target for tumor immunotherapy and diagnosis. We would like to comment on the mesothelin variants diagrammed in Fig. 2 of that article (1). The existence of mesothelin variants with divergent amino acid sequences has been pr...
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ژورنال
عنوان ژورنال: Journal of Leukocyte Biology
سال: 2019
ISSN: 0741-5400,1938-3673
DOI: 10.1002/jlb.2ru1118-422r