Single Nucleotide Polymorphism (SNP) and Its Preview
نویسندگان
چکیده
منابع مشابه
Single Nucleotide Polymorphism (SNP) in the Adiponectin Gene and Cardiovascular Disease
Dear Editor, The recent article by Mohammadzadeh et al.[1] on the latest issue of this Journal showed that the T allele +276G/T SNP of ADIPOQ gene is more associated with the increasing risk of coronary artery disease (CAD) in subjects with type 2 diabetes. Adipocytes were described in myocardial tissue of CAD patients and their role recently discussed[2,3]. Susceptibility to CAD by polymorp...
متن کاملA graphene-based platform for single nucleotide polymorphism (SNP) genotyping.
A facile, rapid, stable and sensitive approach for fluorescent detection of single nucleotide polymorphism (SNP) is designed based on DNA ligase reaction and π-stacking between the graphene and the nucleotide bases. In the presence of perfectly matched DNA, DNA ligase can catalyze the linkage of fluorescein amidite-labeled single-stranded DNA (ssDNA) and a phosphorylated ssDNA, and thus the for...
متن کاملHypothesis driven single nucleotide polymorphism search (HyDn-SNP-S).
The advent of complete-genome genotyping across phenotype cohorts has provided a rich source of information for bioinformaticians. However the search for SNPs from this data is generally performed on a study-by-study case without any specific hypothesis of the location for SNPs that are predictive for the phenotype. We have designed a method whereby very large SNP lists (several gigabytes in si...
متن کاملInvestigating single nucleotide polymorphism (SNP) density in the human genome and its implications for molecular evolution.
We investigated the single nucleotide polymorphism (SNP) density across the human genome and in different genic categories using two SNP databases: Celera's CgsSNP, which includes SNPs identified by comparing genomic sequences, and Celera's RefSNP, which includes SNPs from a variety of sources and is biased toward disease-associated genes. Based on CgsSNP, the average numbers of SNPs per 10 kb ...
متن کاملPublication of stand-alone single nucleotide polymorphism (SNP) discovery data.
In the recent past, several publications have appeared in Drug Metabolism and Disposition that described the results of single nucleotide polymorphism (SNP) discovery projects. The publications were limited to only this aspect of the science and failed to include any studies that extended beyond the discovery phase. No attempt was made to elucidate the possible functional significance of the id...
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ژورنال
عنوان ژورنال: Journal of Cell Signaling
سال: 2016
ISSN: 2576-1471
DOI: 10.4172/2576-1471.1000129