Single injection of basic fibroblast growth factor to treat severe vocal fold lesions and vocal fold paralysis

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Single injection of basic fibroblast growth factor to treat severe vocal fold lesions and vocal fold paralysis.

OBJECTIVES/HYPOTHESIS Severe vocal fold lesions such as vocal fold sulcus, scars, and atrophy induce a communication disorder due to severe hoarseness, but a treatment has not been established. Basic fibroblast growth factor (bFGF) therapies by either four-time repeated local injections or regenerative surgery for vocal fold scar and sulcus have previously been reported, and favorable outcomes ...

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Paediatric vocal fold paralysis.

INTRODUCTION AND OBJECTIVES Vocal fold paralysis (VFP) is a relatively common cause of stridor and dysphonia in the paediatric population. This report summarises our experience with VFP in the paediatric age group. METHODS All patients presenting with vocal fold paralysis over a 12-month period were included. Medical charts were revised retrospectively. The diagnosis was performed by flexible...

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Vocal fold paresis and paralysis.

Diagnosis and treatment of the immobile or hypomobile vocal fold are challenging for the otolaryngologist. True paralysis and paresis result from vocal fold denervation secondary to injury to the laryngeal or vagus nerve. Vocal fold paresis or paralysis may be unilateral or bilateral, central or peripheral, and it may involve the recurrent laryngeal nerve, superior laryngeal nerve, or both. The...

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Migration of Cymetra after vocal fold injection for laryngeal paralysis.

Injection laryngoplasty is a common operative technique used in the management of unilateral vocal fold paralysis. Cymetra is a micronized particulate injectable form of acellular human dermis that is commonly used for vocal cord medialization procedures. We report migration of an intracordal bolus of Cymetra into the medial wall of the pyriform sinus. Histopathology from endoscopic resection o...

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Injection laryngoplasty outcomes in vocal fold paralysis using calcium hydroxylapatite.

OBJECTIVES This study aims to evaluate our injection laryngoplasty experience in patients with unilateral vocal fold paralysis. PATIENTS AND METHODS Sixty-eight patients (32 males, 36 females; mean age 59.5 years; range 27 to 86 years) who were diagnosed with unilateral vocal fold paralysis at our clinic and who underwent injection laryngoplasty using calcium hydroxylapatite between January 2...

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ژورنال

عنوان ژورنال: The Laryngoscope

سال: 2015

ISSN: 0023-852X,1531-4995

DOI: 10.1002/lary.25315