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Inherited peripheral neuropathies: a myriad of genes and complex phenotypes.
Trakhtenbrot L, et al. Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient. Growth-associated gene expression after stroke: evidence for a growth-promoting region in peri-infarct cortex. number and timing of transplantation determine survival of human neural stem cell grafts in stroke-damaged rat brain. Abramsky O, et al. Intraventricular tra...
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31 Sine, S.M. (1997) Identification of equivalent residues in the γ, δ, and ε subunits of the nicotinic receptor that contribute to α-bungarotoxin binding. J. Biol. Chem. 272, 23521–23527 32 Czajkowski, C. and Karlin, A. (1995) Structure of the nicotinic receptor acetylcholine-binding site. Identification of acidic residues in the δ subunit within 0.9 nm of the α subunit-binding site disulfide....
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Understanding the molecular underpinnings of evolutionary adaptations is a central focus of modern evolutionary biology. Recent studies have uncovered a panoply of complex phenotypes, including locally adapted ecotypes and cryptic morphs, divergent social behaviours in birds and insects, as well as alternative metabolic pathways in plants and fungi, that are regulated by clusters of tightly lin...
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While the concept of a gene has been helpful in defining the relationship of a portion of a genome to a phenotype, this traditional term may not be as useful as it once was. Currently, "gene" has come to refer principally to a genomic region producing a polyadenylated mRNA that encodes a protein. However, the recent emergence of a large collection of unannotated transcripts with apparently litt...
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With the rapid development of biotechnologies, many types of biological data including molecular networks are now available. However, to obtain a more complete understanding of a biological system, the integration of molecular networks with other data, such as molecular sequences, protein domains and gene expression profiles, is needed. A key to the use of networks in biological studies is the ...
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ژورنال
عنوان ژورنال: Molecular Psychiatry
سال: 1998
ISSN: 1359-4184,1476-5578
DOI: 10.1038/sj.mp.4000455