Single-Fiber Optical Tweezers for Cellular Micro-Manipulation
نویسندگان
چکیده
منابع مشابه
High-Resolution Optical Tweezers for Single-Molecule Manipulation
Forces hold everything together and determine its structure and dynamics. In particular, tiny forces of 1-100 piconewtons govern the structures and dynamics of biomacromolecules. These forces enable folding, assembly, conformational fluctuations, or directional movements of biomacromolecules over sub-nanometer to micron distances. Optical tweezers have become a revolutionary tool to probe the f...
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Chondrocytes and osteoblasts experience multiple stresses in vivo. The optimum mechanical conditions for cell health are not fully understood. This paper describes the optical and microfluidic mechanical manipulation of single suspended cells enabled by the μPIVOT, an integrated micron resolution particle image velocimeter (μPIV) and dual optical tweezers instrument (OT). In this study, we exam...
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Optical tweezers (OT) have emerged as an essential tool for manipulating single biological cells and performing sophisticated biophysical/biomechanical characterizations. Distinct advantages of using tweezers for these characterizations include non-contact force for cell manipulation, force resolution as accurate as 100aN and amiability to liquid medium environments. Their wide range of applica...
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Optical tweezers provide a versatile tool in biological and physical researches. Optical tweezers based on optical fibers are more flexible and ready to be integrated when compared with those based on microscope objectives. In this paper, the three-dimensional (3D) trapping ability of an inclined dual-fiber optical tweezers is demonstrated. The trapping efficiency with respect to displacement i...
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We have recently applied optical tweezers to study human erythrocyte deformation under various thermal-flow conditions, e.g. flow in an open space. Theoretically, Computation Fluid Dynamics (CFD) has been applied for simulating the complex flow-liposome interaction at different flow velocities. More importantly, both experimental and numerical studies have been carried out to determine the defo...
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ژورنال
عنوان ژورنال: Optics and Photonics News
سال: 2008
ISSN: 1047-6938,1541-3721
DOI: 10.1364/opn.19.12.000042