منابع مشابه
Anti-Jo-1 antisynthetase syndrome.
OBJECTIVE Given a lack of population-based studies, we report an epidemiological-clinic study of anti-Jo-1 antisynthetase syndrome (ASS). PATIENTS AND METHODS To study a retrospective cohort of a single-center from 1980 to 2010. Clinical-laboratory and demographic data were obtained from medical files. All patients fulfilled the Bohan and Peter criteria (1975) and presented anti-Jo-1, articul...
متن کاملAnti Jo-1 myositis. 'Mechanic's hands' and interstitial lung disease.
We report three patients who presented with painful weak muscles, a violaccous rash on the extensor aspect of their hands, elevated muscle enzymes, electromyographic and muscle biopsy findings typical ofpolymyositis. All three patients had anti JoI autoantibodies, 'mechanic's hands' and evidence of interstitial lung disease on CT scan. An incomplete response to corticosteroids was observed in a...
متن کاملCharacterization of dermatomyositis with coexistence of anti-Jo-1 and anti-SRP antibodies.
We describe a patient with dermatomyositis who presented with rapidly developing severe muscle weakness complicated by massive pleural effusion with interstitial lung disease. Myopathological analysis was suggestive of dermatomyositis. This patient showed both anti-Jo-1 and anti-SRP antibodies in serum. To our knowledge, the coexistence of these two myositis-specific autoantibodies (MSA) is con...
متن کاملExpression of BAFF receptors in muscle tissue of myositis patients with anti-Jo-1 or anti-Ro52/anti-Ro60 autoantibodies
INTRODUCTION Anti-Jo-1 and anti-Ro52 autoantibodies are common in patients with myositis, but the mechanisms behind their production are not known. Survival of autoantibody-producing cells is dependent on B-cell-activating factor of the tumour necrosis factor family (BAFF). BAFF levels are elevated in serum of anti-Jo-1-positive myositis patients and are influenced by type-I interferon (IFN). I...
متن کاملAnti-Jo-1 antibody-positive patients show a characteristic necrotizing perifascicular myositis.
Idiopathic inflammatory myopathies can be classified as polymyositis, dermatomyositis, immune-mediated necrotizing myopathy, sporadic inclusion body myositis or non-specific myositis. Anti-Jo-1 antibody-positive patients are assigned to either polymyositis or dermatomyositis suggesting overlapping pathological features. We aimed to determine if anti-Jo-1 antibody-positive myopathy has a specifi...
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ژورنال
عنوان ژورنال: Revista Brasileira de Reumatologia
سال: 2010
ISSN: 0482-5004
DOI: 10.1590/s0482-50042010000500003