Simultaneous Estimation of Solifenacin Succinate and Tamsulosin Hydrochloride in Combined Dosage Form by Using First Order Derivative Spectrophotometric Method

Using first-order derivative techniques, a simple accurate and precise Ultraviolet spectrophotometric method was developed for the determination of solifenacin succinate tamsulosin hydrochloride in combined dosage form. Every solifinacin scanned wavelength region 200-400 nm sampling wavelengths selected were selected. Sampling chosen at 265 (zero crossing succinate) where absorbance important 250 hydrochloride) significant. For succinate, linearity ranged from 10 to 100 μg/ml with correlation coefficient 0.998 2 is 0.9988. The median recovery considered be satisfactory. routine study forms, approach proposed can applied.