Silk Microneedle Patch Capable of On‐Demand Multidrug Delivery to the Brain for Glioblastoma Treatment (Adv. Mater. 1/2022)

Dissolving microneedle patch for transdermal delivery of human growth hormone.

The clinical impact of biotechnology has been constrained by the limitations of traditional hypodermic injection of biopharmaceuticals. Microneedle patches have been proposed as a minimally invasive alternative. In this study, the translation of a dissolving microneedle patch designed for simple, painless self-administration of biopharmacetucials that generates no sharp biohazardous waste is as...

Microneedle patch for immunization of immunocompromised hosts

Influenza virus is a major cause of morbidity and mortality particularly in the immunocompromised host. When compared to the general population, influenzarelated hospitalization rates are four times higher and mortality ten times higher in patients with cancer [1]. The Infectious Diseases Society of America (IDSA) recommends the administration of inactivated influenza vaccine (IIV) annually to ...

Materials and Wireless Microfluidic Systems for Electronics Capable of Chemical Dissolution on Demand (Adv. Funct. Mater. 92015)

Potential Cost-Effectiveness of an Influenza Vaccination Program Offering Microneedle Patch for Vaccine Delivery in Children

OBJECTIVE The influenza vaccine coverage rate of children is low in Hong Kong. Microneedle patches (MNPs) is a technology under development for painless delivery of vaccines. This study aimed to examine the potential clinical outcomes and direct medical costs of an influenza program offering MNP vaccine to children who have declined intramuscular (IM) vaccine in Hong Kong. METHODS A decision ...

Microneedle patches for vaccine delivery

In today's medical industry, the range of vaccines that exist for administration in humans represents an eclectic variety of forms and immunologic mechanisms. Namely, these are the live attenuated viruses, inactivated viruses, subunit proteins, and virus-like particles for treating virus-caused diseases, as well as the bacterial-based polysaccharide, protein, and conjugated vaccines. Currently,...