Silica-based mesoporous nanoparticles for controlled drug delivery
نویسندگان
چکیده
منابع مشابه
Silica-based mesoporous nanoparticles for controlled drug delivery
Drug molecules with lack of specificity and solubility lead patients to take high doses of the drug to achieve sufficient therapeutic effects. This is a leading cause of adverse drug reactions, particularly for drugs with narrow therapeutic window or cytotoxic chemotherapeutics. To address these problems, there are various functional biocompatible drug carriers available in the market, which ca...
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The application of nanotechnology to medicine constitutes a major field of research nowadays. In particular, the use of mesoporous silica and carbon nanoparticles has attracted the attention of numerous researchers due to their unique properties, especially when applied to cancer treatment. Many strategies based on stimuli-responsive nanocarriers have been developed to control the drug release ...
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Recent breakthroughs in the synthesis of mesoporous silica materials with controlled particle size, morphology, and porosity, along with their chemical stability, has made silica matrices highly attractive as the structural basis for a wide variety of nanotechnological applications such as adsorption, catalysis, sensing, and separation. In addition, we and others have discovered that surface-fu...
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This manuscript reviews the recent progress on mesoporous silica nanoparticles as drug delivery systems. Their intrinsic structural, textural and chemical features permit to design versatile multifunctional nanosystems with the capability to target the diseased tissue and release the cargo on demand upon exposition to internal or external stimuli. The degradation rate of these nanocarriers in d...
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ژورنال
عنوان ژورنال: Journal of Tissue Engineering
سال: 2013
ISSN: 2041-7314,2041-7314
DOI: 10.1177/2041731413503357