Signaling Delays Preclude Defects in Lateral Inhibition Patterning
نویسندگان
چکیده
منابع مشابه
Signaling Delays Preclude Defects in Lateral Inhibition Patterning.
Lateral inhibition represents a well-studied example of biology's ability to self-organize multicellular spatial patterns with single-cell precision. Despite established biochemical mechanisms for lateral inhibition (e.g., Delta-Notch), it remains unclear how cell-cell signaling delays inherent to these mechanisms affect patterning outcomes. We investigate a compact model of lateral inhibition ...
متن کاملAbstract Submitted for the Mar15 Meeting of the American Physical Society Signaling Delays Preclude Defects in Lateral Inhibition Pattern
Submitted for the MAR15 Meeting of The American Physical Society Signaling Delays Preclude Defects in Lateral Inhibition Patterning INGMAR RIEDEL-KRUSE, DAVID GLASS, XIAOFAN JIN, Stanford University, Bioengineering — Developmental biology is extraordinarily robust in its ability to self-organize spatiotemporal patterns despite an intrinsically noisy set of parts. Lateral inhibition is a classic...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2015
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2014.11.1700