Siesta: Still an Enigma

Fournier's gangrene, still an enigma.

Nerve growth factor--an enigma still?

Deuel, T. F., Huang, J. S., Proffitt, R. T., Baenziger, J. U., Chang, D. & Kennedy, 9. B. (1981) J . Biol. Chem. 256, 88968899 Fisher, P. B., Boersig, M. R., Graham, G. M. & Weinstein, I. B. (1983) J. Cell. Physiol. 114, 365-370 Frolik, C. A,, Dart, L. L., Meyers, C. A,, Smith, D. M. & Sporn, M. B. (1983) Proc. Natl. Acad. Sci. U.S.A. 80, 3676-3680 Heldin, C.-H., Westermark, B. & Wasteson, A. (...

Feline infectious peritonitis: still an enigma?

Feline infectious peritonitis (FIP) is one of the most important fatal infectious diseases of cats, the pathogenesis of which has not yet been fully revealed. The present review focuses on the biology of feline coronavirus (FCoV) infection and the pathogenesis and pathological features of FIP. Recent studies have revealed functions of many viral proteins, differing receptor specificity for type...

The mercurial nature of neutrophils: still an enigma in ARDS?

The acute respiratory distress syndrome (ARDS) is a life-threatening lung condition resulting from direct and indirect insults to the lung. It is characterized by disruption of the endothelial-epithelial barrier, alveolar damage, pulmonary edema, and respiratory failure. A key feature of ARDS is the accumulation of neutrophils in the lung microvasculature, interstitium, and alveolar space. Desp...

Lymphocytic esophagitis: Still an enigma a decade later

Lymphocytic esophagitis (LE) is a clinicopathologic entity first described by Rubio et al in 2006. It is defined as peripapillary intraepithelial lymphocytosis with spongiosis and few or no granulocytes on esophageal biopsy. This definition is not widely accepted and the number of lymphocytes needed to make the diagnosis varied in different studies. Multiple studies have described potential cli...