Siderocalin fusion proteins enable a new <sup>86</sup>Y/<sup>90</sup>Y theranostic approach
نویسندگان
چکیده
The mammalian protein siderocalin binds hydroxypyridinone complexes of trivalent rare-earth metals and f-elements through cation-π electrostatic interactions. It can also be fused with biological vectors for the targeted delivery imaging therapeutic radionuclides.
منابع مشابه
Personalized NanoMedicine: Towards new Theranostic Approach
Since decades, researchers are seeking novel therapeutic strategies to cure and monitor diseases for personalized health care needs. Numerous successful efforts are being made to design and develop personalized NanoMedicine approach to cure diseases at target site with minimum or no adverse effects. The designing of novel nanomaterials, maximum binding with therapeutic agent, controlled navigat...
متن کاملa new approach to credibility premium for zero-inflated poisson models for panel data
هدف اصلی از این تحقیق به دست آوردن و مقایسه حق بیمه باورمندی در مدل های شمارشی گزارش نشده برای داده های طولی می باشد. در این تحقیق حق بیمه های پبش گویی بر اساس توابع ضرر مربع خطا و نمایی محاسبه شده و با هم مقایسه می شود. تمایل به گرفتن پاداش و جایزه یکی از دلایل مهم برای گزارش ندادن تصادفات می باشد و افراد برای استفاده از تخفیف اغلب از گزارش تصادفات با هزینه پائین خودداری می کنند، در این تحقیق ...
15 صفحه اولA New Approach to Self-Localization for Mobile Robots Using Sensor Data Fusion
This paper proposes a new approach for calibration of dead reckoning process. Using the well-known UMBmark (University of Michigan Benchmark) is not sufficient for a desirable calibration of dead reckoning. Besides, existing calibration methods usually require explicit measurement of actual motion of the robot. Some recent methods use the smart encoder trailer or long range finder sensors such ...
متن کاملNanobody as a new generation of functional proteins
Nanobody (Nb) or VHH is the smallest binding domain of camelid heavy chain antibody (HcAb). Light chains of HcAb naturally removed and because of some evolutionary changes, Nbs have unique properties rather than conventional antibodies. The size of Nb is about one-tenth (0.1) of whole antibodies and this size improved some problems of four chains antibodies such as high yield of expression in p...
متن کاملFusion proteins and fusion pores
A meeting was recently held at the Juan March Foundation in Madrid (22–24 May, 2000) on the topic ‘Regulated exocytosis and the vesicle cycle’. This small discussion meeting brought together speakers using molecular, electrophysiological or a combination of approaches in the study of exocytosis and vesicle retrieval. It was clear from the presentations and discussions that there is now reasonab...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: RSC chemical biology
سال: 2023
ISSN: ['2633-0679']
DOI: https://doi.org/10.1039/d3cb00050h