Should we lower cholesterol as much as possible?: Cholesterol is good?
نویسندگان
چکیده
منابع مشابه
High -density lipoprotein cholesterol as a predictor for diabetes mellitus
Background: Diabetes is a prevalent chronic disease around the world. To evaluate risk of diabetes comprehensively, we developed a score model for the risk prediction with HDL-C as a protective factor. Methods: We extracted physical examination data of 2728 individuals. The data contain 18 demographic and clinical variables. To identify the statistical significant feature variables, the backwa...
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Despite the advances made in the last decade in automated planning, no planner outperforms all the others in every known benchmark domain. This observation motivates the idea of selecting different planning algorithms for different domains. Moreover, the planners’ performances are affected by the structure of the search space, which depends on the encoding of the considered domain. In many doma...
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HMG-CoA reductase inhibitors, or statins, have been shown to decrease all-cause mortality in individuals aged 65 and older with known coronary heart disease (CHD) and elevated cholesterol levels. (Grade of recommendation: A, based on randomized controlled trials.) The clinical benefit of statin use in older persons without known CHD, however, is uncertain. Decisions about testing for lipid leve...
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THREE DECADES AGO, THE PRIMARY RESULTS OF THE MULtiple Risk Factor Intervention Trial (MRFIT) were published in JAMA; that trial attempted to demonstrate benefits from lowering cholesterol (with diet) and managing other known risk factors for reducing cardiovascular morbidity and mortality. Since then, multiple trials have shown cardiovascular benefit from lowering cholesterol, especially low-d...
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More than four decades ago it was established that an elevated low-density lipoprotein-cholesterol level was a risk for developing coronary artery disease. For the last two decades, statins have been the cornerstone of reducing low-density lipoprotein-cholesterol, but despite significant clinical efficacy in the majority of patients, a large number of patients suffer from side effects and canno...
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ژورنال
عنوان ژورنال: BMJ
سال: 2006
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.332.7555.1453