Should we consider subcellular compartmentalization of metabolites, and if so, how do we measure them?

Should We Consider another Booster Dose of Measles Vaccine?

Background: To date, 36 years has passed since the beginning of measles vaccination; the disease is still circulating around the world, threatening lives of human beings especially in developing countries.  In recent years, we have confronted measles in previously vaccinated adults from all over the country. Objective: To find out if there is a need for changing our routine measles vaccination ...

Erythema nodosum :what should we consider about it?

Should we treat pyrexia? And how do we do it?

The concept of pyrexia as a protective physiological response to aid in host defence has been challenged with the awareness of the severe metabolic stress induced by pyrexia. The host response to pyrexia varies, however, according to the disease profile and severity and, as such, the management of pyrexia should differ; for example, temperature control is safe and effective in septic shock but ...

Predicted values: how should we use them?

How Do We Measure Comorbidity?

This chapter reviews methods used to measure comorbidity in the context of cancer; summarising methods, identifying contexts in which they have been used and assessing the validity, reliability and feasibility of each approach. Measures of comorbidity are categorised according to whether they are based on individual conditions or simple counts, on dysfunction/function of organ systems, on condi...