Should Intravenous Thrombolysis be Considered the First Option in Pregnant Women?

Should intravenous thrombolysis be considered the first option in pregnant women?

T he current package insert for tissue plasminogen activator (t-PA) indicates that consideration of its use in pregnancy must include risks weighed against anticipated benefits. Major risks in the current patient include a bad functional outcome from an evolving stroke with a National Institutes of Health Stroke Scale of 12 and known M2 occlusion, risk of intracere-bral hemorrhage from thrombol...

Staphylococcus lugdunensis; a pathogen that should be considered in Iran

Background: Staphylococcus lugdunensis is Gram-positive cocci of the staphylococcaceae family. S. lugdunensis despite having a clotting factor (wall coagulase), was classified in the coagulase negative staphylococcus group (CoNS) for lack of free coagulase. Although this bacterium is part of the human normal flora, in terms of virulence, S. lugdunensis is in second place after S. aureus. S. lug...

Percutaneous closure of prosthetic paravalvular leaks - should it be considered the first therapeutic option?

Paravalvular leak (PVL) is one of the most common complications of surgical implantation of mechanical or biological valve prostheses and, more recently, with percutaneous valve replacement. Its incidence ranges, according to the series, between 2 and 10% for aortic valves and 7 and 17% for mitral valves. Although most patients with PVL have few or no symptoms and are accordingly treated conser...

Basilic vein transposition should be the first option

Should Euthanasia Be Considered Iatrogenic?

As more countries adopt laws and regulations concerning euthanasia, pediatric euthanasia has become an important topic of discussion. Conceptions of what constitutes harm to patients are fluid and highly dependent on a myriad of factors including, but not limited to, health care ethics, family values, and cultural context. Euthanasia could be viewed as iatrogenic insofar as it results in an out...