Shortened Tracer Uptake Time in GA-68-DOTATOC-PET of Meningiomas Does Not Impair Diagnostic Accuracy and PET Volume Definition
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Synchronous bilateral bronchial carcinoid diagnosed with combined dual tracer ((18)F-FDG and (68)Ga-DOTATOC) PET/CT scans.
A 38-year-old non-smoker female with unremarkable history presented with an insidious onset of dry cough. Computed tomography revealed two solid round pulmonary lesions, curiously symmetrically located in the middle lobe and in the lingular segment, respectively (Fig. 1). Trans-bronchial needle biopsy was limited by a profuse bleeding and the diagnosis was inconclusive. The radiological differe...
متن کاملDiagnostic role of Gallium-68 DOTATOC and Gallium-68 DOTATATE PET in patients with neuroendocrine tumors: a meta-analysis.
BACKGROUND Gallium-68 somatostatin receptor positron emission tomography (PET) has been used in the diagnosis of neuroendocrine tumors (NETs). The compounds often used in molecular imaging of NETs with PET are 68Ga-DOTATOC, 68Ga-DOTATATE, and 68Ga-DOTANOC. There is varying affinity to different somatostatin receptors. PURPOSE To systematically review and perform a meta-analysis of published d...
متن کاملIntraarterial treatment of GEP NET: (68)Ga-DOTATOC SUV cannot predict (90)Y-DOTATOC uptake.
Kratochwil and colleagues (1) demonstrate in their very elegant study that selective intraarterial (i.a.) application of Ga-DOTATOC into the feeding artery of liver metastases from neuroendocrine tumors leads to a significantly higher SUV compared with intravenous (i.v.) application. An advantage of their study is the absence of therapeutic interventions as a confounding factor. This is a limit...
متن کاملMeningiomas: A Comparative Study of 68Ga-DOTATOC, 68Ga-DOTANOC and 68Ga-DOTATATE for Molecular Imaging in Mice
PURPOSE The goal of this study was to compare the tumor uptake kinetics and diagnostic value of three (68)Ga-DOTA-labeled somatostatin analogues ((68)Ga-DOTATOC, (68)Ga-DOTANOC, and (68)Ga-DOTATATE) using PET/CT in a murine model with subcutaneous meningioma xenografts. METHODS The experiment was performed with 16 male NUDE NU/NU mice bearing xenografts of a human meningioma cell line (CH-157...
متن کاملGa-68 DOTATATE PET/CT in Neuroendocrine Tumors: Initial Experience
Introduction: Neuroendocrine tumors (NET) are a heterogeneous group of neoplasms, majority of which express somatostatin (SST) receptors. Recently, with the widespread use of positron emission tomography/computed tomography (PET/CT) and development of novel PET tracers like Ga-68 DOTA peptide which specifically bind to somatostatin receptors (SSTR), Ga-68 DOTA peptide PET/CT is used in manageme...
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ژورنال
عنوان ژورنال: Diagnostics
سال: 2020
ISSN: 2075-4418
DOI: 10.3390/diagnostics10121084