Short Read (Next-Generation) Sequencing
نویسندگان
چکیده
منابع مشابه
Read classification for next generation sequencing
Next Generation Sequencing (NGS) has revolutionised molecular biology, allowing routine clinical sequencing. NGS data consists of short sequence reads, given context through downstream assembly and annotation, a process requiring reads consistent with the assumed species or species group. The common bacterium Staphylococcus aureus may cause severe and life-threatening infections in humans, with...
متن کاملART: a next-generation sequencing read simulator
UNLABELLED ART is a set of simulation tools that generate synthetic next-generation sequencing reads. This functionality is essential for testing and benchmarking tools for next-generation sequencing data analysis including read alignment, de novo assembly and genetic variation discovery. ART generates simulated sequencing reads by emulating the sequencing process with built-in, technology-spec...
متن کاملShort Barcodes for Next Generation Sequencing
We consider the design and evaluation of short barcodes, with a length between six and eight nucleotides, used for parallel sequencing on platforms where substitution errors dominate. Such codes should have not only good error correction properties but also the code words should fulfil certain biological constraints (experimental parameters). We compare published barcodes with codes obtained by...
متن کاملNext Generation Sequencing Technologies: A Short Review
When the editorial board invited me to write this short review, I remembered my old dream since thirty years ago, is it possible for mankind to live without more health burden? Scientists can answer a lot of difficult questions like this one. The science is growing very fast and next generation sequencing technologies are currently the hottest topic in the field of human and animal genomics res...
متن کاملCharacterization of a biogas-producing microbial community by short-read next generation DNA sequencing
BACKGROUND Renewable energy production is currently a major issue worldwide. Biogas is a promising renewable energy carrier as the technology of its production combines the elimination of organic waste with the formation of a versatile energy carrier, methane. In consequence of the complexity of the microbial communities and metabolic pathways involved the biotechnology of the microbiological p...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Circulation: Cardiovascular Genetics
سال: 2013
ISSN: 1942-325X,1942-3268
DOI: 10.1161/circgenetics.113.000085