Short footshock-electroconvulsive shock intervals and retrograde amnesia in mice
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چکیده
منابع مشابه
BR-16A restricts development of electroconvulsive shock-induced retrograde amnesia.
Forty nine adult male Sprague Dawley rats were selected for rapid learning in a T-maze to study the effects of BR-16A, a herbal preparation on ECS-induced retrograde amnesia. Half the rats received 200 mg/kg BR-16A and the other half received vehicle alone. The rats were trained to run into the enclosed chamber of either the left or the right arm on a T-maze; a food pellet served as a reward in...
متن کاملPre-electroconvulsive shock administration of calcium channel blockers reduces retrograde amnesia induced by ECS.
Effect of pre-electroconvulsive shock (ECS) administration of calcium channel blockers (CCBs) like verapamil, diltiazem, nifedipine, nimodipine, flunarizine and cinnarizine on retrograde amnesia induced by ECS was examined using passive avoidance paradigm in rats. The groups (Gr 1-7) of adult, male Wistar rats received true ECS with CCBs (5mg/kg; i.p) or vehicle (10 ml/kg; ip) and other groups ...
متن کاملRetrograde amnesia after electroconvulsive therapy: a temporary effect?
OBJECTIVE Although electroconvulsive therapy (ECT) is generally considered effective against depression, it remains controversial because of its association with retrograde memory loss. Here, we assessed memory after ECT in circumstances most likely to yield strong retrograde amnesia. METHOD A cohort of patients undergoing ECT for major depression was tested before and after ECT, and again at...
متن کاملKetamine induces anterograde and retrograde amnesia in rats
Introduction: The N-methyl-D-aspartate (NMDA) receptors, which have been implicated in memory formation, could be noncompetitively blocked by ketamine. The present study examines the short term effect of ketamine on induction of anterograde and retrograde amnesia in male rats using Morris water maze (MWM). Methods: Male N-MRI rats were randomly divided into nine experimental groups. MWM stud...
متن کاملRetrograde amnesia.
In humans, the phenomenon of temporally graded retrograde amnesia has been described in the clinic and the laboratory for more than 100 years. In the 1990s, retrograde amnesia began to be studied prospectively in experimental animals. We identified 13 published studies in which animals were given equivalent training at two or more separate times before damage to the fornix or hippocampal format...
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ژورنال
عنوان ژورنال: Psychonomic Science
سال: 1971
ISSN: 0033-3131
DOI: 10.3758/bf03335838