Short- and long-term predictors of spontaneous bacterial peritonitis in Singapore

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Short-course ceftriaxone therapy in spontaneous bacterial peritonitis.

Forty patients with spontaneous bacterial peritonitis, three of whom had complicating acute hepatitis syndrome, eight late-onset hepatic failure, and 29 with cirrhosis, were treated with ceftriaxone 2 g intravenously once daily for 5 days. Ascitic fluid culture was positive in 28 patients, with Escherichia coli and Klebsiella as common isolates. All the bacteria isolated were sensitive to ceftr...

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Spontaneous bacterial peritonitis.

Spontaneous bacterial peritonitis (SBP) is a common, serious complication in patients with cirrhosis and ascites. It is a bacterial infection of ascitic fluid in the absence of an adjacent, surgically amenable infection source. Since its description in 1964 (1) numerous studies, guidelines, and both national and international consensus conferences have brought significant advancement to the dia...

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["Spontaneous" bacterial peritonitis].

Since its initial description in 1964, research has transformed spontaneous bacterial peritonitis (SBP) from a feared disease (with reported mortality of 90%) to a treatable complication of decompensated cirrhosis, albeit with steady prevalence and a high recurrence rate. Bacterial translocation, the key mechanism in the pathogenesis of SBP, is only possible because of the concurrent failure of...

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Spontaneous Bacterial Peritonitis

at 20% to 40%.4,5 If the patient survives that hospitalization, one-year and two-year mortality rates for those with SBP are approximately 70% and 80%, respectively.3,6–10 Further adding to the inherent morbidity of SBP is its proclivity for recurrence. After an episode of SBP has been successfully cleared with antibiotic therapy, recurrence rates range from 40% to 70% within the first year.3,6...

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ژورنال

عنوان ژورنال: Singapore Medical Journal

سال: 2020

ISSN: 0037-5675

DOI: 10.11622/smedj.2019085