She Tries Her Tongue; Her Silence Softly Breaks

On the Tip of Her Tongue

These lesions on the tongue of a 7-year-old white girl had been present since she was 2. Her physician at that time had diagnosed "geographic tongue." Over the years, the lesions have increased in number, although not in size. The vesicular lesions measure a few millimeters to a centimeter in diameter and are mostly reddish; a few are blue. They are asymptomatic. Minimal bleeding occurs with tr...

Let Music Sound while She Doth Make Her Choice

To attract females during courtship, Drosophila melanogaster males sing songs with motifs of varying temporal structure. In this issue of Neuron, Clemens et al. (2015) identify a song feature indicating male fitness and propose a neural mechanism for how it may be extracted from the auditory signal by female flies.

Terry L. Erwin: She Had a Black Eye and in Her Arm She Held a Skunk

Terry L. Erwin is Curator of Coleoptera at the Smithsonian Institution, National Museum of Natural History, in Washington, D.C. and editor-in-chief of ZooKeys. He generated significant controversy in 1982—which continues to this day—when he published an estimate of 30 million species on Earth, which was substantially more than the nearly one million described species. He was born 1 December 194...

A child playing hide-and-seek runs to the corner of the room and covers her eyes with a pillow while her father counts to ten, believing that if she cannot see her father, then her father cannot see her

Expression of heregulin, phosphorylated HER-2, HER-3 and HER-4 in HER-2 negative breast cancers.

A significant number of HER-2 amplified breast cancers is effectively treated by trastuzumab and further shows receptor-enhanced chemosensitivity. Recent studies have postulated transactivation of HER-2 also in tumors expressing phosphorylated/activated HER-2 (pHER-2) and of the HER-3/HER-4 ligand heregulin (HRG), independent of HER-2 amplification. As a consequence, a subset of tumors without ...