منابع مشابه
Shaping the zebrafish notochord
Cellular reorganization based on active cell motility and adhesion is the major means of morphogenesis in animal embryos, and is particularly elaborated in vertebrates. Nowhere is this fact more clearly shown than in the dorsal mesoderm of gastrulating zebrafish embryos. Here, occurring in the company of both cellular internalization at the blastoderm margin (Carmany-Rampey and Schier, 2001) (R...
متن کاملMutations affecting development of the notochord in zebrafish.
The notochord is critical for the normal development of vertebrate embryos. It serves both as the major skeletal element of the embryo and as a signaling source for the establishment of pattern within the neurectoderm, the paraxial mesoderm and other tissues. In a large-scale systematic screen of mutations affecting embryogenesis in zebrafish we identified 65 mutations that fall into 29 complem...
متن کاملDaam1 regulates the endocytosis of EphB during the convergent extension of the zebrafish notochord.
Convergent extension (CE) movement of cells is one of the fundamental processes that control the organized morphogenesis of tissues and organs. The molecular events connecting the noncanonical Wnt pathway and CE movement, however, are not well understood. We show that subcellular localization of Daam1, an essential component of noncanonical Wnt signaling, changes dynamically during notochord fo...
متن کاملMutations affecting the formation of the notochord in the zebrafish, Danio rerio.
In a large scale screen for mutants with defects in the embryonic development of the zebrafish we identified mutations in four genes,floating head (flh), momo (mom), no tail (ntl), and doc, that are required for early notochord formation. Mutations in flh and ntl have been described previously, while mom and doc are newly identified genes. Mutant mom embryos lack a notochord in the trunk, and t...
متن کاملThe notochord
the paper, I immediately understood that it was going to be possible to use Agrobacterium to make transgenic plants and that would, in turn, create many new opportunities. I concluded that plant molecular genetics was poised to take off and that insight, plus some nudging from Shauna, tipped me over the edge. What is your greatest frustration? I am frustrated by the influence of political organ...
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ژورنال
عنوان ژورنال: Development
سال: 2003
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.00314