Sex-specific responses of bone metabolism and renal stone risk during bed rest
نویسندگان
چکیده
منابع مشابه
Sex‐specific responses of bone metabolism and renal stone risk during bed rest
The purpose of this study was to directly assess sex differences in bone loss, bone biochemistry, and renal stone risk in bed rest. Bed rest simulates some spaceflight effects on human physiology and can be used to address the potential existence of sex-specific effects on bone metabolism and renal stone risk in space. We combined data from the control subjects in five head-down-tilt bed rest s...
متن کاملReduction of renal stone risk by potassium-magnesium citrate during 5 weeks of bed rest.
PURPOSE Exposure to the microgravity environment of space increases the risk of kidney stone formation, particularly for calcium oxalate and uric acid stones. This study was performed to evaluate the efficacy of potassium alkali as potassium-magnesium citrate in reducing renal stone risk and bone turnover. MATERIALS AND METHODS This study was performed as a double-blind, placebo controlled tr...
متن کاملNitrogen metabolism and bone metabolism markers in healthy adults during 16 weeks of bed rest.
BACKGROUND The associations between nitrogen metabolism and bone turnover during bed rest are still not completely understood. METHODS We measured nitrogen balance (nitrogen intake minus urinary nitrogen excretion) and biochemical metabolic markers of calcium and bone turnover in six males before head-down tilt bed rest (baseline), during 2, 10, and 14 weeks of immobilization, and after reamb...
متن کاملMarkers of bone metabolism during 14 days of bed rest in young and older men
OBJECTIVE We aimed at comparing markers of bone metabolism during unloading in young and older men, and to assess countermeasure effectiveness. METHODS 16 older (60±2 years) and 8 younger men (23±3 years) underwent bed rest (BR) for 14 days. A subgroup of the Older performed cognitive training during BR and supplemented protein and potassium bicarbonate afterwards. Biochemical markers of bone...
متن کاملBone metabolism and nutritional status during 30-day head-down-tilt bed rest.
Bed rest studies provide an important tool for modeling physiological changes that occur during spaceflight. Markers of bone metabolism and nutritional status were evaluated in 12 subjects (8 men, 4 women; ages 25-49 yr) who participated in a 30-day -6° head-down-tilt diet-controlled bed rest study. Blood and urine samples were collected twice before, once a week during, and twice after bed res...
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ژورنال
عنوان ژورنال: Physiological Reports
سال: 2014
ISSN: 2051-817X
DOI: 10.14814/phy2.12119