Sex-related survival differences in murine cardiomyopathy are associated with differences in TNF-receptor expression
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چکیده
منابع مشابه
Sex-related survival differences in murine cardiomyopathy are associated with differences in TNF-receptor expression.
Epidemiological evidence suggests that the prognosis of heart failure in women is better than in men. In our murine model of dilated cardiomyopathy arising from cardiac-specific overexpression of TNF-alpha, the 6-month survival rate was significantly better in females than in males. Young female transgenic mice exhibited left ventricular wall thickening without dilatation, whereas age-matched m...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2000
ISSN: 0021-9738
DOI: 10.1172/jci9307