Sex Differences and Sex Steroids in Lung Health and Disease
نویسندگان
چکیده
منابع مشابه
Sex steroids and cardiovascular disease
As men grow older, testosterone (T) levels decline and the significance of this change is debated. The evidence supporting a causal role for lower circulating T, or its metabolites dihydrotestosterone (DHT) and estradiol, in the genesis of atherosclerosis and cardiovascular disease (CVD) in men is limited. Observational studies associate low baseline T levels with carotid atherosclerosis, aorti...
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The adult skeleton is periodically remodeled by temporary anatomic structures that comprise juxtaposed osteoclast and osteoblast teams and replace old bone with new. Estrogens and androgens slow the rate of bone remodeling and protect against bone loss. Conversely, loss of estrogen leads to increased rate of remodeling and tilts the balance between bone resorption and formation in favor of the ...
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Background: The purpose of this study was to examine symptoms of acute coronary syndrom (ACS) with resect to sex differences. Methods: This comparative cross-sectional study was performed on patients older than 20 years with ACS who were hospitalized at cardiac wards. Sampling was performed through stratified sampling on the basis of sex. Five hundred male and female patients me...
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Men and women are alike in many ways. However, there are important biological and behavioural differences between the two genders. They affect manifestation, epidemiology and pathophysiology of many widespread diseases and the approach to health care. Despite our knowledge of these crucial differences, there is little gender-specific health care; the prevention, management and therapeutic treat...
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There is long-standing evidence for gene-by-sex interactions in disease risk, which can now be tested in genome-wide association studies with participant numbers in the hundreds of thousands. Contemporary methods start with a separate test for each sex, but simulations suggest a more powerful approach should be to use sex as an interaction term in a single test. The traits currently with the mo...
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ژورنال
عنوان ژورنال: Endocrine Reviews
سال: 2012
ISSN: 0163-769X,1945-7189
DOI: 10.1210/er.2010-0031