Severe skin reactions associated with cladribine in people with multiple sclerosis
نویسندگان
چکیده
منابع مشابه
Spinal Cord Analysis in People with Multiple Sclerosis
Background. Multiple Sclerosis (MS) is an autoimmune, inflammatory, and chronic disease which, under the effect of the wastes of myelin degradation occurs in the white matter of the brain, spinal cord, and visual nerves. The main complications of this disease are fatigue, muscle cramps, tremor, imbalance, and walking imbalance. Objectives. The purpose of this study is to investigate the spine ...
متن کاملPopulation Pharmacokinetics of Cladribine in Patients with Multiple Sclerosis
PURPOSE The aims of this study were to characterize the concentration-time course of cladribine (CdA) and its main metabolite 2-chloroadenine (CAde), estimate interindividual variability in pharmacokinetics (PK), and identify covariates explaining variability in the PK of CdA. METHODS This population PK analysis was based on the combined dataset from four clinical studies in patients with mul...
متن کاملLeisure of People With Multiple Sclerosis: A Content Analysis
Objectives: Leisure is a domain of life that is very important, particularly for people with neurological disorders. However, due to social and cultural differences, leisure activities have not been studied extensively. The aim of this study is to determine the different factors influencing leisure activities among people afflicted with Multiple Sclerosis (MS) within the framework of Iranian cu...
متن کاملIncreased Circulating miR-10a Levels Associated with Multiple Sclerosis
Background: Multiple sclerosis (MS) is an autoimmune disease that causes chronic inflammation of the central nervous system. MicroRNAs (miRNAs) are small non-coding RNAs 19–24 nucleotides long, which are differentially expressed in different tissues. The role of miRNAs in MS remains unclear. We assessed miR-10a transcript levels in MS patients during recurrence and two months after relapse. Ma...
متن کاملThe Factors Associated With Olfactory Dysfunction in Patients with Multiple Sclerosis
Introduction: An impaired sense of smell has a remarkable impact on the quality of life. It is seen in a variety of neurodegenerative diseases such as Parkinson disease. In this study, we assessed the olfactory function in patients with Multiple Sclerosis (MS) by Sniff Magnitude Test (SMT). Methods: A cross-sectional study was conducted on 48 patients with MS. A questionnaire, including demog...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Multiple Sclerosis and Related Disorders
سال: 2020
ISSN: 2211-0348
DOI: 10.1016/j.msard.2020.102140