Severe hypocalcemia as a cause of transient ischemic attack? A debatable case and evidence from literature

Hypocalcemia and transient ischemic attack (TIA) are different medical disorders; however, limited evidence suggests a possible link between the two. The underlying pathomechanisms by which hypocalcemia may cause cerebrovascular damage difficult to comprehend. aim of study was present an individual experiencing TIA that possibly due severe associated with hypoparathyroidism after total thyroidectomy; explore available its cause-effect relationship through literature. A 68-year-old man presented Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia complaints weakness, especially in right limbs had worsened last week. patient experienced unconsciousness for hour before admission; disorientation anterograde amnesia over time recovering consciousness. Other included frequent muscle cramps, numbness both arms legs, dizziness, swallowing difficulty, nausea, vomiting. history thyroidectomy large struma diffuse 18 years ago prescribed several medications. However, overwhelmed forgetfulness become more recent months resulting medication nonadherence. vital sign stable Chovsteck's positive. Montreal Cognitive Assessment (MoCA) revealed impairment visuospatial/executive component delayed memory. Laboratory tests hypocalcemia, altered thyroid function, hypomagnesemia, elevated D-dimer fibrinogen, vitamin D deficiency. were proposed as diagnosis. Prompt initiation appropriate treatment, including calcium supplementation, anticoagulation, neuroprotective agents, led significant clinical improvement. Evidence from literature there is occurred this patient. studies warrant establish relationship.