Serum Transaminase in Duchenne Dystrophy
نویسندگان
چکیده
منابع مشابه
P164: Adeno-Associated Viral Vectors in Duchenne Muscular Dystrophy
Duchenne muscular dystrophy (BMD) is an inherited X-link disease. The incidence of this muscle-wasting disease is 1:5000 male live births. Mutation in the gene coding for dystrophin is the main cause of BMD. Most cases of this disease succumb to respiratory and cardiac failure in 3rd to 4th decades. The slow progression of BMD and recent achievement of gene therapies make it as an appropriate c...
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Serum biomarkers in Duchenne muscular dystrophy (DMD) may provide deeper insights into disease pathogenesis, suggest new therapeutic approaches, serve as acute read-outs of drug effects, and be useful as surrogate outcome measures to predict later clinical benefit. In this study a large-scale biomarker discovery was performed on serum samples from patients with DMD and age-matched healthy volun...
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0960-8966/$ see front matter 2013 Elsevier B.V. All rights re http://dx.doi.org/10.1016/j.nmd.2013.07.013 We read with interest the recent debate on steroids, growth and motor function decline in Duchenne muscular dystrophy (DMD) [1–3]. The efficacy and safety of growth hormone treatment in 39 ambulant DMD boys with glucocorticoid-induced growth failure was recently evaluated [3]. The authors o...
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The mills of God grind slowly. The medical profession are not far behind. It is almost 40 years since Drachman et al. [1] in an open study of 14 patients with Duchenne dystrophy, aged 3–10 years, for periods ranging from 1 to 28 months, concluded that steroids might have some palliative benefit, and that further studies were needed. Some 14 years later Brooke and his colleagues [2] took up the ...
متن کاملDuchenne muscular dystrophy An overview of Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) affects approximately 1 in 3,500 live male births [1]. It is caused by a large variety of mutations in the dystrophin gene. Because of these mutations, the body can no longer make dystrophin which is a protein important for stabilisation of the muscle cell during a contraction. Without dystrophin, muscle cells are damaged and slowly replaced by fat and scar tis...
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ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 2011
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-25-3-7