Serum Telomerase Levels and COPD Exacerbations
نویسندگان
چکیده
منابع مشابه
Serum Telomerase Levels and COPD Exacerbations.
BACKGROUND To our knowledge, there is no study on the level of telomerase in subjects with COPD during an exacerbation period. The objective of this work was to compare lipid peroxidation, telomerase, zinc (Zn), copper (Cu), and malondialdehyde levels in asymptomatic smokers and subjects with COPD exacerbation. METHODS The study included 45 subjects with COPD exacerbation and 42 healthy subje...
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BACKGROUND The literature is scarce regarding the prevalence and clinical impact of IgG subclass deficiency in COPD. We investigated the prevalence of IgG subclass deficiencies and their association with exacerbations and hospitalizations using subjects from two COPD cohorts. METHODS We measured IgG subclass levels using immunonephelometry in serum samples from participants enrolled in two pr...
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Telomeres are specialized regions of repetitive sequences that found at each end of chromosomes and have an important function in protecting the genomic integrity. In the absence of telomerase functioning in the proliferating cells, every mitotic division progressively shorten telomeres which ultimately leads to senescence of the cells. Therefore, shortening of telomeres’ length is recognized a...
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ژورنال
عنوان ژورنال: Respiratory Care
سال: 2016
ISSN: 0020-1324,1943-3654
DOI: 10.4187/respcare.04389