منابع مشابه
Serum Soluble ST2 and Diastolic Dysfunction in Hypertensive Patients
BACKGROUND Echocardiographic evaluation of left ventricular (LV) structural and functional alterations in hypertension has some limitations, potentially overcome by using biomarkers. ST2, a prognostic biomarker for heart failure and myocardial infarction patients, was less studied in hypertension. AIM To analyze the relationship between serum ST2 levels and diastolic dysfunction (DD) in hyper...
متن کاملPrognostic Value of Soluble ST2 (sST2) Serum Levels in Infants and Children with Heart Failure Complicating Congenital Heart Disease
Background Heart failure (HF) in infants and children with congenital heart disease (CHD) is a crucial complication with different outcomes. Many biomarkers are used as prognostic indicators. Soluble ST2 (sST2) is one of these markers studied in adults with HF. We aimed to study the prognostic value of sST2 in CHD children with HF. Materials and Methods In current case-control study, thirty-six...
متن کاملSerum soluble ST2 as a biochemical marker of acute heart failure: future areas of research.
he investigation into biochemical markers is modifying the pproach to the diagnosis and management of heart failure HF). Over the last decade, natriuretic peptides (NPs) have een shown to be particularly useful in confirming or efuting the diagnosis of HF as well as stratifying long-term isk profiles. Several novel cardiac, metabolic, and inflamatory biochemical markers have emerged in the fiel...
متن کاملIdentification of serum soluble ST2 receptor as a novel heart failure biomarker.
BACKGROUND Using genomic technology, we previously identified an interleukin-1 receptor family member, ST2, as a gene markedly induced by mechanical strain in cardiac myocytes. The soluble receptor form of ST2 is secreted and detectable in human serum. This study tested the hypothesis that soluble ST2 levels in the serum of patients with severe chronic heart failure are increased in patients wi...
متن کاملThe increase in serum soluble ST2 protein upon acute exacerbation of idiopathic pulmonary fibrosis.
BACKGROUND The human ST2 gene can be specifically induced by growth stimulation in fibroblastic cells, and the soluble ST2 protein (ST2) is expressed preferentially in T-helper type 2 (Th2) cells. Furthermore, ST2 is induced by proinflammatory stimuli such as tumor necrosis factor-alpha and interleukin-1 beta. It has been reported that the inflammatory response in idiopathic pulmonary fibrosis ...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2010
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2009.08.047