Serum Prostate-Specific Antigen (PSA) Concentration, PSA Mass, and Obesity

Prostate-Specific Antigen (PSA) Test

• Prostate-specific antigen (PSA) is a protein produced by cells of the prostate gland. The PSA test measures the level of PSA in the blood (see Question 1). • The U.S. Food and Drug Administration (FDA) has approved the use of the PSA test along with a digital rectal exam to help detect prostate cancer in men age 50 and older. The FDA has also approved the PSA test to monitor patients with a h...

Prostate-Specific Antigen (PSA) Best Practice Policy

Introduction The Use of PSA for Early Detection of Prostate Cancer The Use of PSA for Pretreatment Staging of Prostate Cancer The Use of PSA in the Posttreatment Management of Prostate Cancer Methods Used in Best Practice Policy Development References PSA Best Practice Policy Task Force Prostate cancer is the most common form of noncutaneous cancer in men in the United States. Despite its preva...

Clinical Use of Prostate Specific Antigen ( PSA )

Like other countries, Japan is recording a rapid increase in the incidence of prostate cancer. The use of serum PSA (prostate specific antigen) measurement as a blood marker for prostate cancer has become widespread. Higher levels of PSA are associated with a higher probability of a diagnosis of prostate cancer. Needle biopsies detect prostate cancer in 20–30% of cases with PSA levels of 4.1–10...

Prostate-specific Antigen (psa) Screening – Current Views

Variants in the prostate-specific antigen (PSA) gene and prostate cancer risk, survival, and circulating PSA.

An A to G substitution, rs925013, in the promoter of the prostate-specific antigen gene (PSA) was recently found to be associated with promoter activity and circulating PSA levels. The objective of this study was to test the associations between rs925013 and another A to G substitution, rs266882, in the PSA gene with prostate cancer risk using a population-based case-control study of 821 prosta...