Serum PCR Diagnosis of Brucella melitensis Infection in Rev. 1 Vaccinated Sheep

Brucella melitensis Infection in Sheep-dogs in Iran

First Report of Isolation of Brucella melitensis, Vaccine Strain Rev.1 as a Source of Cattle Infection in Iran

Evaluation on stability process of Brucella melitensis - Rev. 1 vaccine in Iran

According to the reports of WHO, stability of Rev.1 vaccine should take more than one year, while the expiring date for the vaccine produced in Iran is 3 to 4 months, therefore any attempt to elongate the stability of this vaccine can solve many problems of the production including the request of Veterinary Organization of Iran in this regard. The objective of this study was to increase the sta...

Brucella melitensis infection in sheep: present and future.

Sheep brucellosis, a zoonosis mainly due to B. melitensis (biovar 1, 2 or 3), remains widespread world-wide. Pathologically and epidemiologically, the disease is very similar to B. abortus infection in cattle. The live B. melitensis Rev 1 strain is currently considered as the best vaccine available for the control of sheep brucellosis, especially when used at the standard dose by the conjunctiv...

Efficacy of several antibiotic combinations against Brucella melitensis Rev 1 experimental infection in BALB/c mice.

OBJECTIVES The objective of the present study was to compare the efficacy of gentamicin given alone or combined with doxycycline with that of standard combination therapies in BALB/c mice experimentally infected with the Brucella melitensis vaccine strain Rev 1. METHODS A standard broth microdilution method was applied to determine the susceptibility of strain Rev 1 to the clinically most rel...